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Targeted Release of a Bispecific Fusion Protein SIRPα/Siglec-10 by Oncolytic Adenovirus Reinvigorates Tumor-Associated Macrophages to Improve Therapeutic Outcomes in Solid Tumors

Summary by Stemwell Science News
To identify the characteristics of recombinant adenovirus-SIRPα/Siglec-10, investigators conducted CCK8 assay, quantitative PCR, western blot, competitive binding assay, in vitro cytotoxicity assay, ELISA and phagocytosis assay. [Journal for ImmunoTherapy of Cancer] Full Article
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Stemwell Science News broke the news in on Friday, April 4, 2025.
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