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Target Choice and Exon Skipping Regulate CRISPR-Directed Gene Editing of NRF2 in Head/Neck and Esophageal Cancer Cells
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Target Choice and Exon Skipping Regulate CRISPR-Directed Gene Editing of NRF2 in Head/Neck and Esophageal Cancer Cells
Investigators disabled specific endpoints of NRF2 in an attempt to restore chemo-sensitivity in head/neck and esophageal cancer cells. They identified two targeting characteristics that regulate the effectiveness of this approach. [Molecular Therapy Oncology] AbstractFull ArticleGraphical Abstract
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