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Syracuse vs. Miami: Early look at odds, college football picks, best bet for Saturday

Summary by Syracuse NY
Syracuse travels to South Florida on Saturday to take on No. 18 Miami at Hard Rock Stadium. The Orange enter the 3:30 p.m. ET matchup on ESPN with a 3–6 record and a five-game losing streak, still searching for consistency on offense. Miami sits at 6–2 and is heavily favored, opening as nearly a four-touchdown favorite at home, though coming off a difficult 26-20 loss at SMU that knocked the Canes’ college football playoff hopes askew.

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Syracuse vs. Miami: Early look at odds, college football picks, best bet for Saturday

Syracuse travels to South Florida on Saturday to take on No. 18 Miami at Hard Rock Stadium. The Orange enter the 3:30 p.m. ET matchup on ESPN with a 3–6 record and a five-game losing streak, still searching for consistency on offense. Miami sits at 6–2 and is heavily favored, opening as nearly a four-touchdown favorite at home, though coming off a difficult 26-20 loss at SMU that knocked the Canes’ college football playoff hopes askew.

·Syracuse, United States
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Syracuse NY broke the news in Syracuse, United States on Wednesday, November 5, 2025.
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