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Study uncovers mechanism for reading extra-long neuronal genes

The protein forms nuclear condensates with long RNAs to coordinate transcription and splicing, and failure of the process reduces gene expression.

Summary by News Medical
Neurons in humans and other mammals express many exceptionally long genes, ranging from more than 100 kb to over 2 Mb, that are important for forming synapses and neural circuits.

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Study uncovers mechanism for reading extra-long neuronal genes

Neurons in humans and other mammals express many exceptionally long genes, ranging from more than 100 kb to over 2 Mb, that are important for forming synapses and neural circuits.

·Mona Vale, Australia
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Tech ExploristTech Explorist

The hidden trick Neurons use to read extra-long genes

Scientists at Ehime University discovered SFPQ condensates that help coordinate transcription and splicing of extra-long neuronal genes.

·India
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Merca2.esMerca2.es

They Discover the Mechanism that Allows Neurons to Read Ultra-Long Genes From 2 Million Bases

Scientists have identified how neurons read genes from more than two million bases without collapsing, a key finding to understand the formation of synapses. La entrada Discover the mechanism that allows neurons to read ultra-long genes from 2 million bases aparece primero en Merca2.

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Neuroscience NewsNeuroscience News

How Neurons Transcribe Massive Genes

Scientists discover RNA-scaffolded SFPQ condensates in neurons that enable the transcription of extra-long genes, providing new insights into ASD and ALS.

·The Woodlands, United States
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News Medical broke the news in Mona Vale, Australia on Tuesday, September 15, 2026.
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