US EditionStudy shows gout medication can reduce risk of heart attack or stroke
A study of 109,504 gout patients found urate-lowering treatment reduced five-year risks of heart attack, stroke, and cardiovascular death when targeting serum urate below 360 µmol/L.
- University of Nottingham researchers found treating gout to target urate levels reduced heart attack and stroke risk in a JAMA Internal Medicine study of nearly 110,000 patients.
- Gout arises from uric acid crystal deposits in joints and has been linked to increased risk of cardiovascular disease including heart attacks and stroke.
- Patients were split into two groups and classed as treat‑to‑target if they reached serum urate target below 360 micromol/L within one year of first allopurinol treatment.
- Those reaching urate under 300 micromol/L saw larger risk reductions, with treat‑to‑target patients having higher survival and lower cardiovascular event risk than non‑T2T patients.
- Professor Abhishek Abhishek led the multi‑country analysis using Clinical Practice Research Datalink Aurum and linked hospital and mortality records from the UK, Sweden and Italy.
30 Articles
30 Articles
Gout warning: Professor shares key signs that ‘small crystals’ are building in your joints
Scientists have discovered that medication commonly used to treat gout could offer an unexpected bonus, offering protection against heart attacks and strokes.The research, conducted by scientists in the UK, Sweden and Italy, has found that patients taking uric acid-lowering drugs, primarily allopurinol, experienced fewer cardiovascular events over a five-year period.The team examined records from more than 109,000 adults diagnosed with gout, whi…
Gout medication can reduce the risk of heart attack and stroke, finds new study
A groundbreaking new study, led by experts at the University of Nottingham, has found that medicines used to treat gout can also reduce the risk of heart attack and stroke in people with gout. The new research, which is published in JAMA Internal Medicine, shows that treating gout to target blood urate levels also prevents heart attacks and stroke. The study is led by Professor Abhishek from the School of Medicine at the University along with co…
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