Study finds epilepsy patients who use cannabis may increase seizures
- On Monday, researchers published a study in the journal Epilepsia linking frequent cannabis use to worsening seizures in patients with drug-resistant epilepsy.
- The team examined medical records of 64 patients, comparing 22 frequent cannabis users, defined as consuming the drug at least 20 times a month, against 42 non-users.
- Frequent users were significantly more likely to experience severe focal to bilateral tonic-clonic seizures at 90% compared to 57% for non-users, and required specialized care just five years after epilepsy onset.
- Researchers suspect high-potency THC, rather than the CBD found in FDA-approved Epidiolex, may worsen symptoms, though the study is observational and cannot demonstrate clear causation.
- Lead researcher Santiago Philibert-Rosas said clinicians should screen epilepsy patients for cannabis use, as future studies will objectively measure consumption to clarify these clinical risks.
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21 Articles
Frequent Cannabis Use Linked to Doubled Seizure Risk, Study Finds
Scientists have found that near-daily cannabis users face roughly double the seizure risk compared to non-users, based on millions of U.S. hospital records from 2016–2019. The association persists after adjustments but does not prove direct causation, highlighting the need for further research into long-term neurological effects.
Study finds epilepsy patients who use cannabis may increase seizures
The research team examined 64 adults with drug-resistant epilepsy.
Frequent cannabis use tied to more severe epilepsy
Adults with hard-to-treat epilepsy who used cannabis most days had more than twice as many convulsive seizures per year and became resistant to antiseizure medications more quickly than nonusers, according to new research from Washington University School of Medicine in St. Louis.
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