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How Does a Bird Virus Infect a Person? Surprising Findings From B.C.’s Human Case of H5N1 Avian Flu

The study used cryo-electron microscopy and other tests to show two spike-protein mutations reduced receptor binding, challenging assumptions about human adaptation.

Summary by The Conversation
How do we know when an animal virus might pose a risk to humans? Canada confirmed a human case of H5N1 avian influenza (often called “bird flu”) in 2024, the first ever known to have been acquired in Canada. The patient, a thirteen-year-old British Columbian, suffered severe symptoms including respiratory failure but recovered with intensive care in hospital. Uncovering insights into how pathogens can switch from animals to humans — as in this h…

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vancouverstar.com broke the news in Vancouver, Canada on Monday, September 28, 2026.
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