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STING Inhibition Differences Revealed Between Humans and Mice
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STING Inhibition Differences Revealed Between Humans and Mice
Researchers have long focused on the Stimulator of Interferon Genes (STING) pathway, a key component of the innate immune system, as an approach to recruit immune cells to target cancer. However, stimulation of the pathway can also exacerbate many inflammatory diseases, emphasizing a need for therapeutic STING inhibition. No STING investigational drugs have advanced into clinical trials due to limited understanding of the pathway’s biochemical m…
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