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Neanderthals Passed on a Gene that Helps Modern Humans Pack on More Muscle — but only a Few People Have It

Adults carrying the variant had about 270 grams more muscle mass per copy, researchers said, with effects appearing mainly after puberty.

  • A study published Aug. 5 in Cell found that a Neanderthal gene variant inherited through interbreeding about 47,000 years ago remains in some humans today, enhancing how cells respond to growth hormone.
  • Recent scientific findings have broadened understanding of Neanderthals as possessing broad ribcages, thick bones and strong muscles suited for hunting Ice Age beasts, providing context for this ancient genetic legacy.
  • Laboratory experiments showed mouse cells with the Neanderthal version of the growth hormone receptor grew about 40 percent more than standard cells; adults carrying the variant averaged about 270 grams additional muscle mass.
  • The variant shows striking geographic variation, appearing in about 1% of people with European ancestry but up to 25% of those with Southern Asian or Southeast Asian ancestry, prompting further investigation.
  • Researchers analyzed more than 1.1 million human genomes alongside ancient DNA from archaeological sites across Europe, the Balkans, Siberia and Asia, finding the variant's effects emerge only during puberty as one possible piece of a larger evolutionary puzzle.
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11 Articles

Lean Left

International scientists have identified an ancient genetic variant that passed from Neanderthals to modern humans and directly affects physical build. Research has shown that individuals carrying this gene are taller and more muscular than those who do not.

·Istanbul, Türkiye
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Right

A Neanderthal gene variant may enhance the effects of growth hormone, and its carriers may be more muscular and taller on average.

·Budapest, Hungary
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An inherited gene variant of the Neanderthals could still have an influence on the physique today. This is shown by a new study.

·Berlin, Germany
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SciencePost broke the news on Sunday, August 9, 2026.
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