Shingles vaccine linked to 24% lower dementia risk
Researchers found 1 dementia case may be prevented for every 17 older adults vaccinated, though the observational study cannot prove Shingrix caused the reduction.
- A study published in the Annals of Internal Medicine on Wednesday found that older adults receiving the recombinant zoster vaccine showed a 24% lower risk of dementia over four years.
- Researchers from Brown University analyzed Medicare claims and electronic health records for over 500,000 older adults admitted to skilled nursing facilities between 2017 and 2022.
- Over a four-year follow-up, dementia developed in 18.8% of vaccinated participants versus 24.6% of those who remained unvaccinated, translating to roughly one dementia case prevented for every 17 people vaccinated.
- Lead author Kaley Hayes noted the findings could support both physical and cognitive health, though researchers emphasize clinical trials are required to confirm if the vaccine directly lowers dementia risk.
- This potential preventive measure may point to broader cognitive benefits for high-risk nursing-home populations, pending further investigation into the vaccine's specific mechanisms of action.
45 Articles
45 Articles
A new shingles vaccine for the elderly reduces the risk of coronary heart disease and other cardiovascular diseases by an average of nine percent, UK researchers have found, a discovery they say could save hundreds of thousands of lives in the future.
With increasing age, the risk of cardiovascular disease increases. Researchers have now demonstrated an amazing side effect of shingles vaccination. To this end, they investigated the data of 70,000 people.
The US switch in shingles vaccines revealed an unexpected heart health pattern
In a natural experiment involving 72,920 propensity-matched US adults aged 60 years and older, recombinant shingles vaccination was associated with a 9% lower cardiovascular disease burden over seven years compared with the live attenuated vaccine. Lower burdens of ischemic heart disease and heart failure were seen in both sexes, while ischemic stroke was significantly lower only among men, supporting further clinical trials and mechanistic stud…
Current shingles vaccine linked to lower risk of coronary heart disease, stroke and heart failure
Shingles is a painful and serious condition affecting many older people. It is caused by the herpes zoster virus, which can flare up in people who previously had chickenpox. A vaccine against shingles (Zostavax) was introduced in 2006. In many countries, including the U.K. and U.S., Zostavax has now been withdrawn and replaced by a much more effective recombinant vaccine (Shingrix). In the U.K., Shingrix is being offered by the NHS to all older …
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