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Shingles vaccine linked to 24% lower dementia risk
Researchers found Shingrix was associated with 18.8% dementia incidence versus 24.6% in unvaccinated patients, or one case prevented for every 17 vaccinated.
- Researchers led by Kaley Hayes at Brown University found that nursing-facility residents receiving Shingrix had a 24% lower risk of dementia over four years, according to a study published yesterday in Annals of Internal Medicine.
- Using Medicare claims and records, researchers analyzed 509,926 people across more than 5,500 skilled nursing facilities between 2017 and 2022. Target trial emulation compared 8,843 residents who received at least one Shingrix dose against unvaccinated participants.
- After four years, dementia developed in 18.8% of vaccinated participants versus 24.6% of those unvaccinated. "This translates to about one in 17 dementia cases potentially being prevented," Hayes said.
- The findings align with earlier research suggesting shingles vaccines offer neuroprotective benefits beyond preventing shingles. Hayes noted the results fit into a larger puzzle showing vaccines support both physical and cognitive health.
- Researchers cannot definitively confirm Shingrix caused the lower dementia risk because vaccinated participants were younger and healthier. Hayes urged clinical trials to establish causation, and the study received funding from GlaxoSmithKline, which had no control over publication.
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Shingles vaccine found to lower risk of heart diseases, strokes
A Nature Medicine study found lower cardiovascular burden in older adults who received Shingrix instead of the older live shingles vaccine. The findings have sharpened interest in benefits beyond shingles prevention, though trials are still needed to confirm any direct effect.
·Noida, India
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The benefits of the Shingrix vaccine, given in two doses, could be comparable to those of daily treatment with blood pressure medications, say researchers. The current vaccine against the zoster zone seems to significantly reduce the risk of myocardial infarction and stroke, according to scientists, who claim that it could contribute to preventing ...
·Romania
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Coverage Details
Total News Sources30
Leaning Left4Leaning Right6Center11Last UpdatedBias Distribution52% Center
Bias Distribution
- 52% of the sources are Center
52% Center
L 19%
C 52%
R 29%
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