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Setmelanotide successfully targeting extreme hunger in PWS trial

Treatment with setmelanotide helped reduce uncontrollable hunger, known as hyperphagia, and also eased anxiety in children and adults with obesity due to Prader-Willi syndrome (PWS). The Rhythm Pharmaceuticals‘ experimental injection therapy was also shown to reduce body fat and preserve lean mass in individuals with PWS. That’s according to six-month interim data from a one-year Phase 2 clinical trial (NCT06772597) that’s evaluating the therapy…
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Prader-Willi Syndrome News broke the news on Thursday, June 18, 2026.
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