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Self-blinking 'fairy lights' allow DNA to be imaged at almost double-helix-width resolution

Summary by Phys.org
Researchers have developed fluorescent molecules that permit imaging of how DNA is packaged inside living cells at unprecedented resolution and, in preserved cells, at a resolution close to the width of the double helix itself.

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A team from the Center for Genomic Regulation has developed fluorescent molecules that allow images of how DNA is packaged into living cells with an unprecedented resolution and, in preserved cells, with a resolution close to the width of the double helix itself. The entry Fluorescent probes allow to obtain DNA images with an unusual resolution was first published in Salud a Diario.

An international team has developed fluorescent molecules that allow to obtain images of DNA in living cells and tissues preserved with a precision of three nanometers, close to the width of the double propeller itself.Published in the journal Molecular Cell, the research -leaded by the Centre for Genomic Regulation (CRG) of Barcelona - introduces probes called HOT that go through the cell membrane alone and allow to capture DNA in its natural s…

·Lima, Peru
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Phys.org broke the news in Douglas, United Kingdom on Friday, August 28, 2026.
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