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Seaport Therapeutics doses first patient in trial of GlyphAllo for depression - Pharmafile

Summary by pharmafile.com
Seaport Therapeutics has dosed its first patient in its phase 2b BUOY-1 study of GlyphAllo (SPT-300), an oral prodrug of allopregnanolone, for the treatment of major depressive disorder (MDD), with or without anxious distress. GlyphAllo is designed using the company’s Glyph platform to overcome bioavailability limitations of allopregnanolone, a molecule known for its rapid antidepressant […] The post Seaport Therapeutics doses first patient in t…
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pharmafile.com broke the news in on Friday, July 25, 2025.
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