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Biomarkers in Blood and Urine May Reveal Energy Intake from Ultraprocessed Foods, Study Finds

  • Erikka Loftfield and colleagues published a study on May 20, 2025, in PLOS Medicine identifying blood and urine markers that reveal ultraprocessed food intake in older U.S. Adults.
  • The study built on data from over 1,000 AARP members collected over a year, addressing challenges in accurately tracking ultraprocessed food consumption.
  • Scientists identified hundreds of metabolites correlated with ultraprocessed food energy intake and developed scores from 28 blood and up to 33 urine markers predicting consumption reliably.
  • Loftfield said the signature is "predictive of this dietary pattern that's high in ultraprocessed food," and Dr. Mozaffarian called the markers "a major scientific advance."
  • These findings may illuminate the biological mechanisms connecting ultraprocessed food intake to health effects, and Loftfield plans to utilize this method with current research involving blood and urine samples to examine cancer risk.
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Sci Tech Daily broke the news in on Monday, May 19, 2025.
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