Scientists Thought SuperAgers Had Lucky Genes. They Were Wrong
A multi-site study of 142 SuperAgers found common Alzheimer’s risk genes and polygenic scores did not distinguish them from average older adults.
6 Articles
6 Articles
These 80-year-olds have the memory of 50-year-olds. Scientists now know why
A rare group of adults over 80, known as SuperAgers, are rewriting what we thought was possible for the aging brain. With memory abilities comparable to people decades younger, their brains either resist or withstand the damage typically linked to Alzheimer’s disease. Decades of research reveal that their social lifestyles and unique brain biology may hold the key to preserving cognitive function. Scientists believe these insights could pave the…
Study of "super movers" suggests exceptional mobility in late life is a powerful marker of brain health
Older adults who maintain exceptionally fast walking speeds into their eighties tend to experience less cognitive decline and have a lower risk of developing cognitive impairment. New research published in the journal Neurology indicates that these individuals, dubbed “super movers,” do not necessarily have less Alzheimer’s-related brain pathology but instead possess structural advantages in the brain that might help them cope with aging. These …
The healthiest super-agers may have one thing in common: stable cognition
A 10-year study of 1,003 older adults linked cognitive super-aging to fewer emergency visits, unplanned hospital admissions, delirium episodes, dementia diagnoses, and residential aged care placements. Maintaining cognitive performance over time showed the strongest overall association with favorable health outcomes and was linked to a 46% lower mortality risk.
Scientists Thought SuperAgers Had Lucky Genes. They Were Wrong
SuperAgers may keep their memories sharp not because they dodged Alzheimer’s genes, but because their brains possess hidden defenses scientists are only beginning to uncover. Some people reach their 80s and 90s with memory abilities that rival, or even surpass, those of adults decades younger. Known as SuperAgers, these exceptional individuals are helping scientists investigate [...]
A recent study suggests that SuperAgers, individuals who maintain exceptional memory skills into old age, possess brain defenses that go beyond simple genetic luck. The research, conducted by scientists at the Healthy Aging & Alzheimer’s Research Care (HAARC) Center at the University of Chicago and the Translational Genomics Research Institute (TGen), analyzes the characteristics that allow these individuals to maintain sharp memories into their…
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