Pancreatic Cancer Cells Continuously Reshape DNA to Evade Treatment

Pancreatic cancer cells continuously reshape DNA to evade treatment

A new analysis of nearly half a million cells from dozens of pancreatic tumors, led by researchers at UC San Diego Moores Cancer Center and New York University (NYU), reveals how pancreatic cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment.

UCSD-led study finds how pancreatic cancer cells can change genetic makeup

Pancreatic cancer cells can reshape their makeup over time, making them one of the most difficult cancers to treat, according to a study published on Tuesday by UC San Diego Moores Cancer Center and New York University.

Single-cell map shows how pancreatic cancer clones evolve to outsmart

Pancreatic cancer has long been one of medicine’s most stubborn adversaries, a disease that shrugs off chemotherapy, resists immunotherapy, and claims the lives of more than 85 percent of patients within five years of diagnosis. Now, a landmark single-cell study led by researchers at UC San Diego Moores Cancer Center and New York University has revealed, in unprecedented detail, why this cancer is so difficult to defeat: it is not one disease be…

Scientists Reveal How Pancreatic Cancer Evolves to Evade Treatment

In landmark single-cell study of pancreatic tumors, UC San Diego Moores Cancer Center researchers reveal how tumor evolution shapes disease, which could yield new, more effective treatments for one of the deadliest cancers.