Japanese Scientists Produce Fertile Female Clones From Male Mice Using CRISPR
7 Articles
7 Articles
Most recently, groundbreaking therapies with the CRISPR gene shear became known – and a dramatic death. What does all this mean for biomedicine?
Japanese Scientists Produce Fertile Female Clones From Male Mice Using CRISPR
Scientists in Japan have achieved a striking feat in reproductive biology. They created female clones from male mouse cells by excising the Y chromosome. The resulting mice developed normally, reached adulthood, and produced offspring when bred. But this isn’t simple cloning. The work sidesteps long-standing barriers in mammalian sex determination. It opens fresh questions about conservation, genetic diversity, and the future limits of assisted …
Cloning could be used to save species—or make human “organ sacks”
(MIT Technology Review) – This week I spoke to scientists who have found a way to turn male mouse embryos female. They’ve developed a CRISPR-based approach to essentially cut out the Y chromosome. It allowed them to create female clones of male mice. That’s right: female animals that are genetically identical to males, except for the missing Y chromosome. Takashi Ishiuchi, a reproductive biologist at the University of Yamanashi who co-led the wo…
The research group was able to remove the Y chromosome in male mice embryos. Thus they produced female clones. They hope that the technique of gender reading on t3n.de
In 2009, a Japanese laboratory was cloning male mice as a routine operation. Of the twenty-seven pups, however, one was female. They hadn't planned it: it had happened by mistake, and no one had given it much thought. Sixteen years later, Takashi Ishiuchi and Shogo Matoba decided to do it on purpose and figure out how to replicate it every time, precisely, using CRISPR to eliminate the Y chromosome before the clone developed. The result is a pre…
Coverage Details
Bias Distribution
- 100% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
