Double-Pronged Attack on Advanced Prostate Cancer Shows Promise
The drug combination targets tumours with PTEN-loss/PI3K activation and could benefit 40% of advanced prostate cancer patients, offering new hope against hormone-resistant disease.
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7 Articles


Double-pronged attack on advanced prostate cancer shows promise
Patients could one day be treated with the new combination of drugs.
A combination of drugs could help treat up to 40% of patients in the late stages of advanced prostate cancer.
Scientists have found particular types of the disease could be vulnerable to this double-pronged attack. The drugs involved are already used to treat other cancers - and can help slow tumour growth and kill off cancer cells. Dr Adam Sharp, from The Institute of Cancer Research in Sutton, thinks this approach could be used more widely. https://audioboom.com/posts/8791587-dr-adam-sharpe-from-icr-sutton
Prostate Cancer Therapy Effectiveness Boosted by Combination with Enzyme Inhibition
An international study led by scientists at Flinders University and at South China University of Technology has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men. The preclinical in vitro and in vivo study found that two protein disulfide isomerase (PDI) enzymes—PDIA1 and PDIA5—are involved in androgen receptor (AR) regulation, and play a crucial role in help…
Scientists reveal new method that could treat patients with advanced prostate cancer – UK Times
Sign up for our free Health Check email to receive exclusive analysis on the week in health Get our free Health Check email Get our free Health Check email Scientists have found a new method that could treat patients with advanced prostate cancer. Experts at The Institute of Cancer Research, London, found that a two-pronged method could help treat as many as 40 per cent of patients with late-stage disease. Using drugs that are already being used…
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