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Scientists Engineer Precision Tool For Mitochondrial DNA Manipulation - Data Intelligence
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Scientists Engineer Precision Tool For Mitochondrial DNA Manipulation - Data Intelligence
A research team at Fujita Health University has developed a precision genome-editing approach to modulate levels of mutant mitochondrial DNA (mtDNA) in patient-derived stem cells, offering a new method to study mitochondrial diseases and potentially inform future therapeutic strategies. The findings, published in Molecular Therapy Nucleic Acids, center on engineered enzymes known as mpTALENs—mitochondria-targeted transcription activator-like eff…
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