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Sanofi, Regeneron Expand DUPIXENT Alliance in Deal Worth Up to €8 Billion

The companies will split development costs and future profits evenly as the pact adds four early-stage antibody drugs targeting immunological diseases.

  • On Thursday, Sanofi and Regeneron Pharmaceuticals announced an expanded partnership including a $1 billion upfront payment and up to $7 billion in milestone payments to develop four new antibody drugs.
  • The four antibody drugs target the same type 2 inflammation pathways as Dupixent, with REGN20423 currently in early-stage testing for atopic dermatitis and three others expected to begin clinical testing in 2027.
  • Regeneron will lead research and development while Sanofi spearheads global sales efforts; the companies will share costs equally and split future Profits from these potential products.
  • The agreement marks an early success for CEO Belen Garijo, who took Sanofi's top role in May; the deal also settles litigation and addresses investor concerns regarding Dupixent's patent expiration.
  • Jefferies analyst Michael Leuchten described the expansion as a positive signal of Sanofi's proactive focus on addressing key investor uncertainties and demonstrating speed of progress in immunology.
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DECRYPTAGE - The French laboratory, which has to replenish its portfolio of medicines, spends up to €8 billion.

·Paris, France
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Pharmacists Sanofi and Regeneron have concluded an agreement to expand their strategic alliance in the co-development and global marketing of new immunology drugs, in a transaction with a potential value of up to US$ 8 billion for the American partner. Exclusive material for subscribers. To have full access, access the link of the material and register.

·Rio de Janeiro, Brazil
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WTVB broke the news on Thursday, October 1, 2026.
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