Evolutionarily recent retrotransposons contribute to schizophrenia
5 Articles
5 Articles
Evolutionarily recent retrotransposons contribute to schizophrenia
Transposable elements (TEs) are mobile genetic elements that constitute half of the human genome. Recent studies suggest that polymorphic non-reference TEs (nrTEs) may contribute to cognitive diseases, such as schizophrenia, through a cis-regulatory effect. The aim of this work is to identify sets of nrTEs putatively linked to an increased risk of developing schizophrenia. To do so, we inspected the nrTE content of genomes from the dorsolateral …
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