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Roche Strikes Obesity Drug Licensing Deal Worth up to $1.16 Billion with Chinese Rona Therapeutics

  • On Tuesday, Swiss drugmaker Roche entered a licensing agreement worth up to $1.16 billion with Rona Therapeutics for its investigational obesity drug candidate, ALK7.
  • Seeking to challenge the market dominance of Eli Lilly and Novo Nordisk, Roche aims to leverage Rona's proprietary RNAi platform to develop novel metabolic therapies.
  • The deal provides Rona with an upfront payment of $100 million, while the firm remains eligible for up to $1.06 billion in potential milestone payments and tiered royalties.
  • CEO and Founder Stella Shi called ALK7 a "compelling obesity and metabolic disease target" with potential to selectively reduce visceral fat while preserving lean mass.
  • Unlike therapies working in the CNS, ALK7 inhibition acts directly on adipose tissue biology, creating potential for independent use or combination with established obesity treatments.
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13 Articles

Lean Right

Roche has concluded an agreement with the Chinese Rona Therapeutics to license the global rights of an experimental therapy against obesity and metabolic diseases for up to $1.16 billion. Exclusive material for subscribers. To have full access, access the link of the material and register.

·Rio de Janeiro, Brazil
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Lean Right

With the partnership, the pharmaceutical group secures a worldwide license for active ingredients against obesity. This pushes Roche further to the lucrative market for weight loss preparations.

·Düsseldorf, Germany
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ReutersReuters
+3 Reposted by 3 other sources
Center

Major drugmakers turn to China for licensing deals

·London, United Kingdom
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PR Newswire broke the news in Chicago, United States on Tuesday, October 13, 2026.
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