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A self-assembling nanoplatform for pyroptosis and ferroptosis enhanced cancer photoimmunotherapy

Summary by Nature
The microenvironment of immunosuppression and low immunogenicity of tumor cells has led to unsatisfactory therapeutic effects of the currently developed nanoplatforms. Immunogenic cell death, such as pyroptosis and ferroptosis, can efficiently boost antitumor immunity. However, the exploration of nanoplatform for dual function inducers and combined immune activators that simultaneously trigger pyroptosis and ferroptosis remains limited. Herein, …

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NatureNature

A self-assembling nanoplatform for pyroptosis and ferroptosis enhanced cancer photoimmunotherapy

The microenvironment of immunosuppression and low immunogenicity of tumor cells has led to unsatisfactory therapeutic effects of the currently developed nanoplatforms. Immunogenic cell death, such as pyroptosis and ferroptosis, can efficiently boost antitumor immunity. However, the exploration of nanoplatform for dual function inducers and combined immune activators that simultaneously trigger pyroptosis and ferroptosis remains limited. Herein, …

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BIOENGINEER.ORGBIOENGINEER.ORG

Revolutionary Nanoplatform Enhances Cancer Treatment Through Self-Assembly

Recent advances in cancer therapy have witnessed a transformative approach through a novel treatment called photoimmunotherapy, which synergistically combines phototherapy with immunotherapy. This innovative treatment modality aims to selectively target and eliminate malignant cells, providing a promising alternative to conventional cancer therapies. In an intriguing development, researchers have introduced a cutting-edge nanotechnology platform…

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BIOENGINEER.ORG broke the news in on Wednesday, February 19, 2025.
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