Researchers uncover new clues about the origin of Alzheimer's tau tangles

Inside Alzheimer's neurons, tau may set off a genetic chain reaction that ends in cell death

Alzheimer's disease is a neurodegenerative disease characterized by a progressive decline in mental functions and memory loss. Along with frontotemporal dementia and some other neurodegenerative disorders, Alzheimer's disease has been associated with an accumulation inside neurons of abnormal clumps of a protein called "tau."

Researchers uncover new clues about the origin of Alzheimer's tau tangles

Researchers at Columbia University have uncovered new clues about the earliest molecular events that may trigger Alzheimer's disease, shedding light on how toxic tau filaments begin to form in the brain.

What did Alzheimer’s origins study find?

Researchers at Columbia University reported new clues about how Alzheimer’s disease may begin at the molecular level—specifically by identifying earlier molecular events that could precede the clinical symptoms. What was studied The work focuses on “the earliest molecular events” that may trigger…