Scientists Find a Weak Spot in One of the Deadliest Brain Cancers
5 Articles
5 Articles
They may have found a weak point in glioblastoma. Researchers say that blocking a protein could make the tumor more sensitive to treatment.
Scientists find a weak spot in one of the deadliest brain cancers
Researchers may have found a new way to weaken glioblastoma’s defenses against treatment. Blocking a protein called SET prevented tumors from forming in preclinical models, while targeting related proteins made cancer cells more vulnerable to radiation. The strategy works by restoring activity of PP2A, an enzyme that glioblastoma cells appear to suppress. Human testing will be needed to determine whether the approach is safe and effective.
Research in the USA found the weak point of glioblastoma tumor. The defense of cancer cells was destroyed by blocking the SET protein. This method can multiply the effect of radiotherapy and chemotherapy.
Blocking the protein SET prevented tumors from forming in mice and made glioblastoma cells more sensitive to radiotherapy. The study is preclinical. The article Glioblastoma, found a weakness that makes it more fragile is taken from Future Next.
Researchers at Ohio State University Cancer Center have identified a new approach to weaken the defenses of glioblastoma, one of the deadliest cancers. Blocking the SET protein has been shown to prevent tumor formation in preclinical models, while targeting related proteins has increased the vulnerability of cancer cells to radiation. Identification of the SET protein as a therapeutic target: The SET protein has been identified as a promising th…
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