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Reproducible Detection of Antigen-Specific T Cells and Tregs via Standardized and Automated Activation-Induced Marker Assay Workflows
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Reproducible Detection of Antigen-Specific T Cells and Tregs via Standardized and Automated Activation-Induced Marker Assay Workflows
Reliable detection of antigen-specific T cells is critical to understand immune responses to infection and vaccination, with translational potential to monitor T cell responses across diverse clinical settings. Activation-induced marker (AIM) assays offer a variety of advantages over methods such as ELISPOT and tetramers but are limited by methodological heterogeneity between research groups and lack of standardized protocols, and AIM assay repr…
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