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Rectal cancer deaths in older millennials are rising rapidly

Researchers found rectal cancer deaths rose 2 to 3 times faster than colon cancer deaths among adults 20 to 44 and are projected to keep climbing through 2035.

  • Rectal cancer deaths among adults aged 20 to 44 are accelerating, with mortality rates rising 2 to 3 times faster than colon cancer, according to a study presented at Digestive Disease Week 2026.
  • Lead author Mythili Menon Pathiyil, gastroenterology fellow at SUNY Upstate Medical University, notes the surge is not hereditary; researchers suggest potential microbiome disruption linked to childhood sugar-sweetened beverage consumption.
  • Younger patients face a seven-month diagnostic delay from symptom onset to treatment, contributing to poor outcomes; 75% of individuals under age 50 are diagnosed at an advanced stage.
  • Dr. Arif Kamal of the American Cancer Society suggests primary care providers must investigate early symptoms in patients under age 45, with patients explicitly asking doctors about potential colon cancer if bowel function changes.
  • By 2035, rectal cancer deaths could exceed colon cancer deaths if current trends continue. Andreana Holowatyj, assistant professor of hematology and oncology at Vanderbilt University Medical Center, stressed the need to understand tumor characteristics to improve treatment.
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Bias Distribution

  • 56% of the sources lean Left
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NBC Bay Area broke the news in San Francisco, United States on Wednesday, April 22, 2026.
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