Giants vs. Rams Prediction, Odds, Spread, Injuries, Trends for NFL Week 2

Rams, Giants looking to build on disparate Week 1 showings when they meet on Monday night

LOS ANGELES (AP) — The Los Angeles Rams could not have looked worse, while the New York Giants could not have looked better in their respective season openers.

Monday Night Football predictions, picks, odds for Rams vs Giants game

Los Angeles Rams vs New York Giants picks, predictions, odds, win probabilities for NFL Week 2 Monday Night Football game on Sept. 21, 2026. Who wins?

Giants vs Rams prediction, odds and TV channel for Monday night

The Giants and Rams face off in Week 2 of the NFL season. Here's how to watch and our prediction for Monday night in Los Angeles.

Rams’ legend warns ‘you can’t just show up’ ahead of Week 2 vs Giants

Andrew Whitworth calls the Rams’ ugly loss to the 49ers a wake-up call and warns their star-studded roster still has plenty of work to do ahead of the Week 2 game against the Giants

Giants at Rams: Predictions, picks and odds for NFL Week 2 game

The Los Angeles Rams host the New York Giants at SoFi Stadium on Sept. 21 and USA TODAY's NFL experts have locked in their picks for the action.

Giants vs Rams odds, point spread, moneyline, total for game Monday

Los Angeles Rams vs New York Giants odds for NFL Week 2 game betting, including point spread, moneyline, over/under for Monday, Sept. 21, 2026.