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Psychedelics tune the brain to the environment

Researchers found 62 volunteers’ brain activity changed with resting, music, meditation and film, suggesting psilocybin’s effects depend on setting and focus.

Summary by Nature
Nature, Published online: 19 August 2026; doi:10.1038/d41586-026-02377-9Rather than just scrambling neural activity, the psychedelic substance psilocybin also reorganizes brain dynamics so as to align with a person’s context and experiences.

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A team of researchers from Australia shows that the consumption of substances such as psilocybin does not generate 'mental chaos' but connects brain regions that normally function separately.

·Barcelona, Spain
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The active ingredient in "magic mushrooms" doesn't simply confuse the brain. The substance, called psilocybin, actually focuses brain activity more effectively on what is happening at any given moment, as a new study in the journal "Nature" shows.

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Nature broke the news in London, United Kingdom on Wednesday, August 19, 2026.
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