Psychedelics alter neurochemical signals tied to hunger and mood in the hypothalamus

Psychedelics alter neurochemical signals tied to hunger and mood in the hypothalamus

New research published in the Journal of Psychopharmacology has found that a single dose of psilocybin leads to widespread changes in gene expression for several neuropeptides in the rat hypothalamus, while ketamine has a more limited effect. The findings suggest that these psychedelics may influence systems involved in mood, appetite, and stress regulation through different molecular pathways in the brain. Psilocybin and ketamine are both psych…