US EditionProtein plays unexpected dual role in protecting brain from oxidative stress damage
BVRA protects neurons by regulating NRF2 to activate antioxidant genes, offering potential new treatments for neurodegenerative diseases like Alzheimer's, researchers say.
3 Articles
3 Articles
Protein plays unexpected dual role in protecting brain from oxidative stress damage
New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.
Protein Plays Unexpected Dual Role in Protecting Brain from Oxidative Stress Damage
New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.
Antioxidant Defense System in the Brain Discovered
A new study identifies biliverdin reductase A (BVRA) as a crucial enzyme defending neurons from oxidative stress, acting independently of its traditional role in bilirubin production. Using genetically modified mice, researchers found that BVRA binds directly to NRF2, a master regulator of antioxidant defense, ensuring the activation of protective genes that maintain cellular health.
Coverage Details
Bias Distribution
- 100% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium
