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Protein Language Model Hits Undruggable Targets, No Structure Required

Pranam Chatterjee, PhD, assistant professor of bioengineering at the University of Pennsylvania (UPenn), emphasizes that text is all you need for artificial intelligence (AI) models to effectively learn the basis of language.  “I give ChatGPT a sentence, but I don’t say ‘this is a noun’ and ‘that’s a verb.’ The model is not trained on the metadata of the text,” explained Chatterjee in an interview with GEN. “The same analogy goes for proteins. Y…

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GEN - Genetic Engineering and Biotechnology News… broke the news in on Thursday, August 14, 2025.
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