Protein-binding affinity model expands role of AI in drug discovery
6 Articles
6 Articles
Protein-binding affinity model expands role of AI in drug discovery
Understanding how molecules interact is central to biology: from decoding how living organisms function to uncovering disease mechanisms and developing life-saving drugs. In recent years, models like AlphaFold changed our ability to predict the 3D structure of proteins, offering crucial insights into molecular shape and interaction.
Inspired by Viral Spike Proteins, Multimeric Aptamers Target Protein Complexes with Precision
Synthetic and inexpensive to produce, aptamers are attractive alternatives to antibodies for biomedical diagnostics and therapeutics. When new aptamer binders are needed, for example, to detect a new virus, they are developed from libraries of millions of nucleic acid sequences. Until now, such libraries contained only monovalent binders. But this contrasts with the structure of many real-world proteins, including the SARS-CoV-2, influenza, and …
Diamond Light Source to help UK become world leader in drug discovery - Harwell Campus
Back Diamond Light Source to help UK become world leader in drug discovery June 10, 2025 Share Tweet Life sciences and health, National facilities People around the world are set to benefit from new breakthroughs in AI-driven drug discovery to tackle previously untreatable diseases and transforming patient outcomes using British AI and research expertise. Announced today, the UK’s ‘OpenBind’ consortium w…
Protein Therapeutics Account for Nearly Half of Top-Selling Drugs Globally in 2023
Protein therapeutics have significantly transformed the […] The post Protein Therapeutics Account for Nearly Half of Top-Selling Drugs Globally in 2023 first appeared on GeneOnline News. The post Protein Therapeutics Account for Nearly Half of Top-Selling Drugs Globally in 2023 appeared first on GeneOnline News.
Understanding how molecules interact is at the heart of biology: decoding the functioning of living organisms to discover the mechanisms of the disease and develop vital drugs. In recent years, models like Alphafold have changed our ability to predict the 3D structure of proteins, providing crucial information on the shape of proteins.
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