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Royal tragedy as Luxembourg’s Prince Frederick dies aged 22

Prince Frederik of Luxembourg died at the age of 22 from PolG mitochondrial disease, as announced by his father, Prince Robert of Luxembourg.
Prince Robert described Frederik as the family's 'superhero' and noted his unique ability to inspire and lead by example.
Frederik was born with the disease, which was diagnosed at age 14, leading to progressive health issues and ultimately his death.
Henri, Grand Duke of Luxembourg, remembered Frederik fondly, stating, 'Part of his superpower was his ability to inspire and to lead by example.

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Il Fatto Quotidiano

'Difficult to diagnose, it affects multiple organs and leaves no way out': what is Polg, the rare genetic disorder that killed Prince Frederick of Luxembourg

The young Prince Frederick of Luxembourg left on March 1 at 22 years old, just eight years after the diagnosis of the rare genetic disorder he suffered from. This was announced by a long letter published in the last few hours by his father, Roberto di Lussemburgo, who fondly remembers him as a superhero, who never lacked a smile and a sense of humor despite the tragic conditions. “It is with a very heavy heart that my wife and I want to inform y…

5 hours ago·Rome, Italy

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The South African

Luxembourg’s Prince Frederik passed away at the age of 22

Prince Frederik of Luxembourg, the youngest son of Grand Duke Henri’s cousin Prince Robert of Luxembourg and Princess Julie of Nassau, has passed away at the young age of 22 in Paris, France. Who announced the passing of Prince Frederik? According to PEOPLE, Prince Frederik passed away on March 1, 2025. The news was announced by the prince’s father through the website of the POLG Foundation. The POLG Foundation was founded by Frederik himself. H…

1 day ago·Johannesburg, South Africa

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TrendingPolitics

Royal Prince Passes Away At Just 22

Prince Frederik of Luxembourg, the youngest son of Prince Robert of Luxembourg and Princess Julie of Nassau, has died at the age of 22. The young royal passed away on March 1 in Paris, France, after a courageous battle with POLG mitochondrial disease, a rare genetic disorder. His father, Prince Robert, who is a first cousin of Grand Duke Henri of Luxembourg, announced the heartbreaking news on the website of the POLG Foundation, the nonprofit or…

1 day ago

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Denver Gazette

Prince Frederik of Luxembourg, 22, dies of rare genetic condition

Prince Frederik of Luxembourg has died of the rare genetic disease he was born with 22 short years ago after saying goodbye to his family on Rare Disease Day Feb. 28.

2 days ago

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NBC News

Prince Frederik of Luxembourg dies at 22 from rare mitochondrial disease

Prince Frederik of Luxembourg died at 22 after years of struggling with the rare mitochondrial disease PolG, according to a statement issued by his parents, Prince Robert and Princess Julie, on Monday.

2 days ago·United States

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Marie Claire

Luxembourg's Royal Family Reveals Prince Frederik Has Died From a Rare Disease at Age 22

Prince Frederick of Luxembourg has died at 22 years old, after being diagnosed with POLG mitochondrial disease as a child, the Royal Family has announced

2 days ago

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