Potential therapeutic strategy for Alzheimer's disease improves efficiency of learning and recall

Potential therapeutic strategy for Alzheimer's disease improves efficiency of learning and recall

Researchers have found evidence that a therapeutic strategy which makes the brain work more efficiently to learn and recall memories may in fact help to target compromised brain activity in Alzheimer's disease. The study led by University of Galway focused on nerve cells which routinely limit or restrict activity and messages being sent by the brain, rather than the more conventional approach of therapy for nerve cells which stimulate activity.

GABA-Based Target for Alzheimer’s Therapy Identified

Researchers at the University of Galway have found evidence that targeting inhibitory signaling in the brain may help address cognitive dysfunction in Alzheimer’s disease (AD), a finding that runs counter to current therapeutic approaches that focus on influencing excitatory pathways. The research, published in Neuropharmacology, identifies how modulation of gamma-aminobutyric acid (GABA) signaling can restore disrupted neural balance and improv…