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Scientists Map Genetic Profile of Cancer in Pet Cats, Find Similarities to Human Disease
Researchers sequenced nearly 1,000 cancer genes from 500 cats, finding mutations in over 50% of tumors that mirror human cancers, aiding precision medicine for both species.
- Scientists analyzed tumor DNA from nearly 500 domestic cats, discovering key genetic mutations linked to cancer that mirror those found in humans, suggesting shared biological processes allow tumors to grow and spread in both species.
- The household cat could hold clues to understanding certain types of breast cancer, such as triple negative breast cancer, as cats develop this subtype more frequently than humans, providing access to samples and potential treatment insights.
- Over 50% of the cat tumors had changes in the FBXW7 gene, which in human breast cancer is associated with worse prognosis, highlighting similarities between cat and human cancers that could lead to new preventative and treatment approaches.
63 Articles
63 Articles
According to a new study, cats could help us better understand cancer in humans because cats are, like dogs, "excellent models for us".
A report published on 19 February in the journal "Science" reveals that there are similarities between tumours contracted by humans and their pets. A step forward that would allow cancers to be better treated, the authors announce.
The results observed in cats in the treatment of cancer could not only bring about changes in veterinary medicine, but could also point the way to a new direction in the treatment of human breast cancer.
New research results could enable earlier diagnoses as well as more targeted therapies for people and cats with cancer.
The largest genetic map of cancer in cats opens the door to treatments shared with humans
Cats, along with dogs, are the animals that spend the most time with humans. They share spaces, routines, and even illnesses. They are exposed to almost all the same environmental stressors that induce tumors in people. However, unlike what happens with dogs, cancer research in felines is very limited. Now, a huge study published in Science, using hundreds of tumor samples, has obtained the most complete oncogenome of the domestic cat. Among its…
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