Less than two years after stopping obesity drugs, weight and health issues return, study finds
Oxford researchers found people regain weight at 0.4 kg per month after stopping GLP-1 drugs, with health benefits reversing in about 1.4 years, urging long-term obesity management.
- On Thursday, University of Oxford researchers found stopping GLP-1 injections leads to rapid weight regain within less than two years and reverses cardiometabolic improvements.
- GLP-1 receptor agonists mimic a gut hormone, stimulating insulin, slowing stomach emptying and reducing appetite, but when treatment stops, biological drivers return, prompting rapid weight regain, Dr Adam Collins said.
- A meta-analysis of 37 clinical trials pooling 9341 participants found average treatment time 10 months and average follow-up eight months, with 8.3kg weight loss during treatment.
- Cost and access issues mean the NHS caps semaglutide at two years, while almost two million British adults used the jabs last year, Jebb said, `One would expect that these treatments need to be continued for life.`
- Separate analyses warn that long-term strategies, including behavioural support, are essential since Garron Dodd states, 'This new data makes it clear they are a starting point, not a cure.
111 Articles
111 Articles
Weight Loss Jab Users Regain Pounds Rapidly After Stopping Treatment, Major Review Confirms
Stopping weight loss drugs leads to rapid weight regain. Heart health benefits reverse just as quickly after ending medication. Weight returns much faster after drugs than after lifestyle changes. Experts state these medications likely require lifelong use to be effective. This creates a permanent financial burden for individuals and health systems. (Natural News)—The brutal reality behind the blockbuster weight loss injection craze is coming in…
According to a study, the so-called jojo effect is particularly pronounced after the end of a treatment with so-called weight loss syringes. An overview study in the British Medical Journal with data from more than 9,000 people shows that those who dropped the drug were on average back at baseline within less than two years - four times faster than those who had relied on healthy nutrition and exercise.
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