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Dire Wolves Lived in Indiana, but Should We Bring Them Back?

  • Colossal Biosciences successfully revived the dire wolf by breeding two males in October 2024 and a female in January 2025.
  • The project followed the dire wolf's disappearance from North America about 13,000 years ago, using advanced DNA and gene-editing techniques.
  • The process combined ancient DNA from specimens up to 72,000 years old with genomic editing and reproductive technology to produce healthy dire wolf puppies.
  • Ben Lamm, CEO of Colossal, explained that their team extracted genetic material from ancient remains dating back thousands of years—a tooth around 13 millennia old and a skull approximately 72 millennia old—to successfully create healthy dire wolf pups.
  • This achievement marks a historic moment in de-extinction science, signaling potential advances in conservation and biotech with plans to revive species like the woolly mammoth by 2028.
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Dire wolves lived in Indiana, but should we bring them back?

A biotechnology company's recent announcement that it had revived a wolf species that went extinct 10,000 years ago is both generating excitement and raising questions about efforts to conserve wild animal populations and the environment.

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WILD Magazine broke the news in on Friday, May 16, 2025.
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