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A New Genetic Test May Be Able to Predict Obesity in Early Childhood. What to Know
INTERNATIONAL, JUL 22 – Researchers developed polygenic risk scores using genetic data from over 5 million people to identify children at higher obesity risk and enable early preventive lifestyle measures.
- On July 21 in Nature Medicine, a study published July 21 in the journal Nature Medicine, involving more than 600 scientists from 500 institutions, used data from over five million people.
- Association between genetic score and BMI before age five, Assistant Professor Roelof Smit observed, 'timing that starts well before other risk factors.'
- Despite wider genomic samples, predictions were better in European ancestry, with the risk score explaining about 17.6% of obesity risk in European groups.
- Researchers stress PGS use must include ethical safeguards, and careful attention to population differences when identifying high-risk children and adolescents.
- Future applications of PGS could include drug therapies and prevention, as the World Obesity Federation expects more than half the global population to be overweight or obese by 2035.
24 Articles
24 Articles
Can Your DNA Predict Your Weight Years Before You Gain It?
A groundbreaking new study has revealed that your DNA may predict whether you’re likely to develop obesity—years before symptoms emerge. Using genetic data from over five million people, scientists created a highly accurate polygenic risk score that signals obesity risk from early childhood. The score is so predictive that signs often appear before age five, [...]
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New genetic test predicts obesity before you start kindergarten
A groundbreaking study involving genetic data from over five million people has uncovered how our DNA can predict obesity risk as early as childhood. The new polygenic risk score outperforms previous methods, helping to identify high-risk children before weight issues develop paving the way for early lifestyle interventions.
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