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FDA Approves Tryptyr Eye Drops for Dry Eye Disease

  • In 2025, Tryptyr, a new eye drop targeting dry eye disease, received regulatory approval in the United States.
  • This approval followed limited existing treatments that have slow onset, poor adherence, and patient dissatisfaction.
  • Tryptyr acts as a TRPM8 receptor agonist, stimulating corneal nerves to quickly increase natural tear production.
  • Phase 3 trials involving over 930 patients showed Tryptyr increased tear production by 42.6% at day 14 compared to 8.2% for vehicle.
  • Alcon plans to launch Tryptyr in the U.S. in the third quarter of 2025, offering a new direct treatment for tear deficiency in dry eye disease.
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FDA Approves Tryptyr Eye Drops for Dry Eye Disease

MONDAY, June 2, 2025 (HealthDay News) -- The U.S. Food and Drug Administration has approved the first-in-class TRPM8 receptor agonist Tryptyr (acoltremon ophthalmic solution) for the treatment of signs and symptoms of dry eye disease.

·Missoula, United States
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pressreach.com broke the news in on Sunday, June 1, 2025.
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