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Northwestern Surgeons Keep Man Alive 48 Hours Without Lungs Using Artificial System
A 33-year-old man survived 48 hours without lungs using an artificial lung system developed by Northwestern surgeons before receiving a double lung transplant.
- On January 29, the journal Med reported a 33-year-old man survived 48 hours without lungs while an external artificial-lung system supported his circulation and oxygenation.
- The patient developed acute respiratory distress syndrome triggered by influenza virus worsened by bacterial pneumonia including drug-resistant Pseudomonas aeruginosa, leading to septic shock and heart and kidney failure.
- Bharat's team engineered an external artificial-lung system that oxygenated blood, removed carbon dioxide, and maintained stable blood flow through the heart, reducing clot risk compared with prior extracorporeal devices.
- Two days later, donor lungs became available and surgeons performed a double lung transplant, with the patient returning to daily life and good lung function more than two years later.
- Molecular analysis showed widespread scarring and immune damage in removed lungs, indicating irreversible tissue damage, and Ankit Bharat said this provides proof that some patients with severe ARDS need transplants while the approach remains limited to highly specialized centers.
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One patient survived two days at the interval between the removal of the patient lungs and the time when it became healthy for transplantation.
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Coverage Details
Total News Sources31
Leaning Left6Leaning Right5Center9Last UpdatedBias Distribution45% Center
Bias Distribution
- 45% of the sources are Center
45% Center
L 30%
C 45%
R 25%
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