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Scientists Create Lab-Grown Blood Cells Using 'Hematoids'
Hematoids replicate early blood formation and produce diverse blood cell types, offering new ways to study leukemia and advance personalized regenerative therapies, researchers said.
- On October 13, 2025, University of Cambridge scientists created three-dimensional embryo-like structures called hematoids that produce blood cells, published in Cell Reports.
- Using self-organizing human stem cells, the model mimics natural development without extra protein cocktails and forms three germ layers within days.
- Under the microscope, researchers observed that by day eight, beating heart cells appeared, and by day thirteen, red patches of blood were visible in the hematoids; said Dr. Jitesh Neupane, `It was an exciting moment when the blood red color appeared in the dish—it was visible even to the naked eye.`
- Researchers say hematoids could help screen drugs and model blood disorders such as leukaemia, while enabling production of long-lasting blood stem cells for personalized therapies using a patient's own cells.
- Cambridge has patented the method through Cambridge Enterprise, and because hematoids derive from reprogrammed adult cells, they enable diverse individual-specific genetic studies with ethics committees' approval.
23 Articles
23 Articles
Cambridge Scientists Grow Human Blood Cells in Lab
Researchers at the University of Cambridge say they have produced human blood cells in the laboratory by using self-organizing, embryo-like structures. Credit: Berkshire Community College Bioscience Image Library – Public Domain via Flickr. Researchers at the University of Cambridge say they have produced human blood cells in the laboratory by using self-organizing, embryo-like structures that mimic key steps of very early human development. The…
Blood stem cells grew in the embryo-like formations, which it is hoped can later be used in leukemia therapy.
Observador
SIC NotíciasTridimensional structures can produce long-term blood stem cells for transplants. However, researchers point out that they cannot be converted into real embryos.
Without the possibility of reaching complete embryos, they have used human stem cells to produce structures similar to blood cells. Some scientists expose limitations to this advance Read
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