New Imaging Technique Reveals Mitochondrial Activity Inside Live Animals

Flicker-assisted localization microscopy reveals altered mitochondrial architecture in hypertension

Mitochondrial morphology is central to normal physiology and disease development. However, in many live cells and tissues, complex mitochondrial structures exist and morphology has been difficult to quantify. We have measured the shape of electrically-discrete mitochondria, imaging them individually to restore detail hidden in clusters and demarcate functional boundaries. Stochastic “flickers” of mitochondrial membrane potential were visualized …

New imaging technique reveals mitochondrial activity inside live animals

In this study, researcher developed a new imaging approach that combines two powerful techniques to solve this problem. First, a special type of microscope called a two-photon microscope is used, which can look deep into live tissues with minimal damage.

New imaging technique monitors protein changes in cancer cells without dyes

Researchers from Helmholtz Munich and the Technical University of Munich have developed a novel method to track cancer treatment responses in individual cells—without the need for dyes or labels.

Breakthrough Imaging Technique Reveals Mitochondrial Dynamics in Living Tissues

In this study, researcher developed a new imaging approach that combines two powerful techniques to solve this problem. First, a special type of microscope called a two-photon microscope is used, which can look deep into live tissues with minimal damage.

New Imaging Method Tracks Multiple Myeloma Treatment Success

Researchers at the biomedical research center Helmholtz Munich in Germany have developed a label-free imaging method that can track whether or not a multiple myeloma treatment is working in single cells. This can help physicians make personalized therapy adjustments based on the cancer’s response to treatment.  Multiple myeloma is the third most common blood cancer, with incidences on the rise. It affects a type of white blood cell, called plasm…