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Lithium Deficiency Linked to Alzheimer's Onset, Orotate Restores Memory in Mice

UNITED STATES, AUG 6 – Harvard researchers found lithium orotate reversed Alzheimer's symptoms in mice, reducing plaques by 70% and restoring memory, suggesting potential for low-dose treatment trials.

  • Researchers at Harvard found that lithium could potentially prevent Alzheimer’s disease by maintaining normal brain function and preventing the buildup of amyloid plaques and tangles.
  • The compound lithium orotate reversed Alzheimer’s pathology in mice and appeared to protect brain health.
  • Prof Bruce Yankner stated that lithium deficiency could be a cause of Alzheimer’s, suggesting a new therapeutic approach for the disease.
  • Low levels of lithium were linked to inflammation and memory loss in mice, according to findings published in Nature.
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Scientists say it may be possible to protect aging brains from Alzheimer's with lithium

Discover groundbreaking research from Harvard Medical School revealing lithium's critical role in brain health, aging and potential Alzheimer's treatments.

·Milwaukee, United States
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Nature broke the news in United Kingdom on Wednesday, August 6, 2025.
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