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New Cholesterol-Lowering Strategy Silences PCSK9, Avoiding Statin Side Effects
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New Cholesterol-Lowering Strategy Silences PCSK9, Avoiding Statin Side Effects
Researchers from the University of Barcelona and the University of Oregon say they have found a way to control levels of low-density lipoprotein cholesterol (LDL-C). This may prevent it from accumulating in the arteries without the side effects seen from statin-based medications. The new method, detailed in a study published in Biochemical Pharmacology, inhibits PCSK9 gene expression using polypurine hairpins (PPRHs) to increase LDL receptor lev…
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