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New breath test could quickly diagnose bacterial infections
UCSF researchers created a portable breath test detecting bacterial infections in 10 minutes using carbon-13–tagged sugars, potentially enabling faster diagnosis and treatment monitoring.
- Researchers at the University of California, San Francisco, developed a breath test that identifies bacterial infections in just 10 minutes, enabling rapid diagnosis for patients in Emergency Room and Acute Care settings.
- Current diagnostic tools, including blood tests and cultures, are often slow, expensive, or non-specific. Professor David Wilson noted that patients and providers need immediate answers to inform treatment decisions.
- In initial animal experiments, the team analyzed carbon-13-labeled carbon dioxide using 'nondispersive infrared spectroscopy,' successfully detecting pneumonia and bone, muscle, and blood infections within 10 minutes.
- Wilson added that the sugar and sugar alcohols used are safe for humans, and E. coli models suggest the method could monitor antibiotic treatment effectiveness as bacterial levels decrease.
- Research published in ACS Central Science outlines the prototype, marking a significant step toward portable, rapid breath-based testing that could replace current slow, non-specific diagnostic methods.
19 Articles
19 Articles
Breath Test Detects Broad Range of Bacterial Infections Within 10 Minutes
Researchers have developed a breath test that can detect bacterial infections in the lungs, blood, muscles, and bone. In a study published today in ACS Central Science, the test successfully detected the presence of pathogenic bacteria such as E. coli or S. aureus in mice, opening the door for a new generation of fast and affordable infection tests. “Accurately and quickly distinguishing invasive bacterial infection from viral illnesses and non…
Prototype Breath Tests Spot Bacterial Infections in Minutes
Infectious diseases are a major cause of death worldwide, and diagnosing bacterial infections remains a challenge in medicine. And doing so reliably is more important than ever, given the increasing frequency of antibiotic resistance.
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