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Neurogene announces treatment intended to reverse HLH associated with high-dose AAV - BioTuesdays
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Neurogene announces treatment intended to reverse HLH associated with high-dose AAV - BioTuesdays
Neurogene (NASDAQ:NGNE) has announced an oral presentation at the American Society of Gene and Cell Therapy (ASGCT) annual meeting this week describing a monitoring and treatment algorithm intended to reverse the rare, severe hyperinflammatory syndrome hemophagocytic lymphohistiocytosis (HLH) that has been associated with systemic exposure to high doses of adeno-associated virus (AAV) gene therapy (>1E14 vg/kg). According to Neurogene, early mon…
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