Improving the Predictive Power of Mouse Models

Improving the predictive power of mouse models

Comparative studies that integrate genetically diverse mouse models and in vitro cell-based assays will accelerate drug discovery for precision medicine.

Mouse models for ultra-rare disorder could pave the way for nervous system gene editing therapies

Scientists at The Jackson Laboratory (JAX) have developed mouse models that survive premature death and enable pre-clinical testing of alternating hemiplegia of childhood (AHC), a devastating and sometimes fatal neurological disorder that affects about one in a million children with no current treatment.