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More than a million to be prescribed weight loss drug to prevent heart attacks and strokes

The weekly injection will be prescribed with diet and exercise after trials showed a 20% lower risk of major heart events.

  • On Wednesday, April 1, 2026, the National Institute for Health and Care Excellence issued final draft guidance recommending semaglutide to reduce heart attack and stroke risks for overweight patients with cardiovascular disease.
  • NICE based its decision on the SELECT study, which demonstrated that semaglutide reduced cardiovascular death risk by almost 20% over about 3.3 years among 17,604 participants.
  • Patients with a body mass index of 27 or higher qualify for the treatment, with health service officials estimating 1.2 million people across England could benefit from the new guidance.
  • Dr. Sonya Babu-Narayan, clinical director at the British Heart Foundation, called semaglutide an "important medicine" for preventing deadly complications, while NHS England's Helen Williams said the treatment could be "life-changing" for high-risk patients.
  • Health service officials suggest the treatment could be available "within months," though experts note prescribing requires targeted implementation including physical activity support to manage potential side effects and muscle loss.
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For patients with a BMI above 27 and who are at high risk of cardiovascular disease.

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ITV broke the news in London, United Kingdom on Tuesday, March 31, 2026.
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